10 Best Warframe Secondary Weapons (2025)

Earlier, we wrote Warframe Weapon Tier List, ranking all weapons from best to worst. But today, we will talk about a handful of secondary weapons to help you select the right ones.

Warframe’s Best Secondary Weapons

The following list is based on our personal choice. You might find some other weapons better than these ones and that is okay. This is because the choice varies from player to player.

First, let’s quickly look at the Comparison between the Best Secondary Weapons in the game:

Sporelacer

The Sporelacer is a Kitgun Shotgun that can be used as both a primary weapon and a secondary weapon. However, it functions differently in both scenarios.

For instance, when used as a primary weapon, the Sporelacer offers a full-auto mode. But in the secondary slot, it works like a semi-automatic shotgun. Overall, it is a great weapon that is perfect for close-range scenarios.

Tenet Diplos

Next up on our list is the Tenet Diplos, a duo of automatic pistols that are extremely deadly. The weapon has a magazine size of 92 bullets and its rounds work well against both armor and shields.

Furthermore, the Tenet Diplos has an aimed fire mode that locks on to 8 enemies at once and fires directly at them. Overall, the Tenet Diplos is an amazing secondary weapon with a high-status chance and critical multiplier. The main thing which makes this weapon worth picking is the fact that it can reload itself while holstered, something that only a few weapons can do in Warframe.

Euphona Prime

The Euphona Prime is my personal favorite shotgun sidearm because of its two firing modes. The first mode lets the weapon fire a slug that can reach a great distance, thus making it ideal for long-range scenarios. As for the second mode, its spread is wider which makes it ideal for close-ranged scenarios.

Therefore, with the touch of a button, you can transform this weapon into something that suits the situation. Furthermore, as it’s a shotgun, its rounds are effective against shields and armor. Its accuracy is also amazing, but only when aiming.

Also Check: Best Weapons in Terraria

Athodai

The Athodai is easily one of the most powerful secondary weapons because of different reasons. It is a hand cannon that can fire powerful beams towards its targets. However, the thing that makes this weapon a solid choice is a feature that increases the fire rate of the weapon if the user manages to land a headshot with it.

Furthermore, you’ll also get to enjoy infinite ammo if you get a headshot. The Athodai also has an alternate fire mode, which becomes unavailable when you’re enjoying the perks of landing a headshot. Overall, the weapon is amazing and there isn’t any reason why you shouldn’t give it a try.

Kuva Twin Stubbas

Another pair of full-auto pistols that we would like to mention is the Kuva Twin Stubbas. The weapon happens to be the biggest one in terms of magazine size on our list as it can store 114 bullets. Furthermore, it offers high slash and impact damage, meaning that it works well against shields and health.

The Kuva Twin Stubbas have a good fire rate and offer amazing accuracy so that you don’t miss any of your shots. Overall, it is easily one of the best sidearms to use in Warframe and you should definitely give it a shot.

Kuva Brakk

The Kuva Brakk is the Kuva version of the Brakk shotgun sidearm. This variant offers a much better status chance and critical chance. In fact, it offers the highest status chance among all secondary shotguns available in the game. Furthermore, its fire rate is also better than the regular variant and it can store more bullets in its magazine than it.

Since it offers high-impact damage, the Kuva Brakk is a weapon you can trust against shields. Its fast reload speed and high damage output makes it one of the deadliest best secondary Warframe weapons. The only downside about this weapon is its high recoil, but that won’t matter much once you learn how to control it.

Tenet Cycron

The original Cycron pistol deals Radiation damage, but this Tenet version of it deals Heat damage instead. In addition to this, this variant offers a better critical chance and status chance.

The critical chance it offers is the third-highest among all secondary weapons in the game. In addition to this, it also does more damage than the regular variant. The Tenet Cycron fires a powerful beam and its pint point accuracy helps you land it accurately on the target. The beam also has the ability to chain between a total of two enemies.

Also Read: Far Cry 6 Best Weapons

Epitaph

The Epitaph is easily the coolest-looking sidearm on our secondaryweapons list. It is a wrist-mounted sidearm that can fire explosive slabs. As it can do impact damage as well, the weapon can easily destroy shields. It can fire both charged and uncharged shots, with both having their own advantages.

For instance, uncharged shots have guaranteed Cold proc and can explode in an 8-meter radius. As for charged shots, they offer the highest critical chance. Overall, the Epitaph is a strong weapon that can help you take down even the toughest of opponents.

Pyrana Prime

Being a Prime variant of the Pyrana shotgun sidearm, the Pyrana Prime offers high critical status, a longer range, and increased clip size. However, the Prime Variant might have its own advantages but they come at the cost of slow fire rate and decreased damage. Despite this, the weapon is still one of the best sidearms to use in the game. It has an excellent reload speed and a high critical chance.

The most interesting thing about this weapon is that after you perform three quick kills with it, you get an ethereal Pyrana in your other hand that stays for a couple of seconds. Overall, the Pyrana Prime is an excellent sidearm for close-range combat.

Kuva Nukor

Finally, we have the Kuva Nukor. This weapon is considered the best secondary weapon by many. This is mainly because it offers the highest critical multiplier in the entire game, combined with pinpoint accuracy and decent damage per shot.

Just like the Tenet Cycron, the beam fired from the Kuva Nukor can also chain between multiple enemies. And for those wondering what is the best DPS secondary weapon in Warframe, it is the Kuva Nukor. Overall, there isn’t any secondary weapon that can come close to this one. Therefore, there isn’t any reason why you shouldn’t try it.

This was our best secondary weapons guide. We hope that it will help you select the right weapons for combat.